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An Important Announcement From

RENASSIST will not reopen in 2018, but will remain open through December 21, 2017.

See Important Dates

Indication

Renvela® (sevelamer carbonate) is used to control phosphorus levels in adults and children 6 years of age and older with chronic kidney disease (CKD) on dialysis.

Renagel® (sevelamer hydrochloride) is indicated for the control of serum phosphorus in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

Do not use Renvela or Renagel if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate or sevelamer hydrochloride or to any of the ingredients in Renvela or Renagel.

Click here for additional Important Safety Information.

Please see Full Prescribing Information for Renvela (PDF) or Full Prescribing Information for Renagel (PDF). Please see Full Prescribing Information for Sevelamer Carbonate (PDF).

Glossary

Blood pressure

The measure of pressure of the blood within your arteries. High blood pressure is when the force of the blood against your artery walls is high enough that it may lead to problems like heart disease.

Calcium

There is more calcium than any other mineral in the body. It is an important part of your diet, and works with phosphorus to keep bones and teeth strong. Calcium also plays a role in maintaining normal heart, nerve, and muscle function in the body.

Chronic kidney disease (CKD)

The loss of kidney function over the course of a few years. CKD Stage 5 is severely reduced kidney function, also called end-stage renal disease (ESRD). People with CKD Stage 5 need dialysis or a transplant to do the work that their kidneys can not.

Dialysis

The process of cleaning waste from the blood artificially. The kidneys normally do this job, but if they aren’t working, the blood must be cleaned with special equipment. The 2 major forms of dialysis are hemodialysis and peritoneal dialysis.

Hemodialysis

The removal of excess fluids and waste from the blood by a machine. This helps to do the work of the kidneys after they have failed. Hemodialysis is the most common form of dialysis and is generally done at a dialysis center.

Kidneys

Most people have two kidneys. These organs clean the excess fluid and waste from your blood. The excess fluids and waste then leave the body in the form of urine. The kidneys also regulate the amount of important chemicals and minerals in your body.

Metabolic

This refers to the many chemical processes related to metabolism. Metabolism consists of the buildup and breakdown of substances in the body.

Parathyroid hormone (PTH)

PTH plays an important role in the absorption of calcium in your body.

Peritoneal dialysis

A process that uses dialysate (a cleansing liquid) and the lining of the your abdominal cavity to clean waste and excess fluid from the blood. Peritoneal dialysis can be done at home.

Phosphate binders

A type of medicine that binds to phosphorus in your digestive system.

Phosphorus

A mineral that plays an important role in maintaining healthy bones. It is found in all tissues in your body and is an important part of metabolic processes in the body.

Sevelamer

The active ingredient of Renvela® (sevelamer carbonate). Sevelamer can help control phosphorus in your blood to help get your minerals in balance. It does not contain calcium or metal and is not absorbed, so it does not build up in your body.

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Renvela®

Indication

Renvela® (sevelamer carbonate) is used to control phosphorus levels in adults and children 6 years of age and older with chronic kidney disease (CKD) on dialysis.

Renagel® (sevelamer hydrochloride) is indicated for the control of serum phosphorus in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

  • Do not use Renvela or Renagel if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate or sevelamer hydrochloride or to any of the ingredients in Renvela or Renagel.
  • Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation.
  • The most common side effects with sevelamer include vomiting, nausea, diarrhea, upset stomach, abdominal pain, flatulence, and constipation.
  • Cases of itching, rash, fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported.
  • Uncommon cases of difficulty swallowing the Renagel or Renvela tablet have been reported. Talk to your doctor if you have difficulty swallowing medicines in tablet form. Renvela powder for oral suspension may be considered by your doctor if you have a history of difficulty swallowing.
  • Your doctor should monitor bicarbonate and chloride blood levels.
  • Reduced vitamins D, E, and K (clotting factors) and folic acid blood levels may be followed by your doctor.
  • Talk to your doctor when taking sevelamer with other medications.
  • Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on sevelamer.
  • Take sevelamer with meals and adhere to your prescribed diet

Sevelamer carbonate

Indication

Sevelamer carbonate is used to control phosphorus levels in adults and children 6 years of age and older with chronic kidney disease (CKD) on dialysis.

Important Safety Information

  • Do not use sevelamer carbonate if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate, sevelamer hydrochloride or to any of the ingredients.
  • Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation.
  • The most frequently occurring side effects with sevelamer carbonate tablets include nausea and vomiting.
  • Side effects with sevelamer carbonate powder taken three times a day are similar to those reported for sevelamer carbonate tablets.
  • The most common side effects with sevelamer include vomiting, nausea, diarrhea, indigestion, abdominal pain, flatulence, and constipation.
  • Cases of itching, rash, fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported.
  • Uncommon cases of difficulty swallowing with sevelamer carbonate tablet have been reported. Talk to your doctor if you have difficulty swallowing medicines in tablet form. Sevelamer carbonate for oral suspension may be considered by your doctor if you have a history of difficulty swallowing.
  • Your doctor should monitor your bicarbonate and chloride blood levels.
  • Reduced vitamins D, E, and K (clotting factors) and folic acid blood levels may be followed by your doctor.
  • Talk to your doctor when taking sevelamer carbonate with other medications.
  • Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on sevelamer carbonate.
  • Take sevelamer carbonate with meals and adhere to your prescribed diet.

Please see Full Prescribing Information for Renvela (PDF) or Full Prescribing Information for Renagel (PDF).
Please see Full Prescribing Information for Sevelamer Carbonate (PDF).
Click here to learn more about Sanofi's commitment to fighting counterfeit drugs.

The health information contained herein is provided for general education purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.

Dear Customer,

Sanofi recently launched its own authorized generic of Renvela (sevelamer carbonate). This means that, in addition to branded Renvela (sevelamer carbonate), patients can now access Sanofi’s authorized generic sevelamer carbonate, depending on their plan coverage.

Due to the change in the market, the need for patient support services has changed. Renassist will remain open through December 21, 2017, but will not reopen in 2018. What this means for healthcare professionals and patients:

  • Multiple Patient Submissions will be accepted through December 1, 2017.
  • Insurance verification requests will be accepted through December 15, 2017.
  • New Renvela Patient Assistance Applications (uninsured patients) will be accepted through December 1, 2017.
    • Patients eligible for refills for this program will be accepted through December 15, 2017.
  • 2017 Part D Assistance Program will close November 15, 2017.
    • Patients eligible for refills for this program will be accepted through December 15, 2017.
  • RenValue card will continue to be available to eligible patients in 2018 where permitted by law.

We would like to thank you for allowing us to support your patients over the years.

Sincerely,

The Team

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