Important Safety Information

Do not use Renvela if you have a history of bowel obstruction. Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation. View Important Safety Information.

Kidney Disease and Dialysis

If you have chronic kidney disease (CKD), it is important for you to understand more about the disease and how you can work with your healthcare professional to manage it.

When you have CKD, your kidneys can’t filter fluids and waste very well because they aren’t healthy. As a result, your body has a hard time keeping the right balance of fluids, minerals, and other substances. As your fluids and minerals become unbalanced, you may experience health problems.

When you have CKD and are on dialysis, an important step in managing your CKD is going to dialysis regularly as instructed by your healthcare professional. Dialysis helps your body by getting rid of excess waste products from your blood. Without dialysis, your body can’t filter fluids and waste properly.

With the right tools and support, you and your healthcare professional can manage your CKD.

Indication for Renvela

Renvela (sevelamer carbonate) is used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

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Indication

Renvela (sevelamer carbonate) is used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

  • Do not use Renvela if you have a history of bowel obstruction
  • Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation
  • Uncommon cases of bowel obstruction and perforation have been reported. Your doctor should monitor bicarbonate and chloride blood levels. Vitamins D, E, K (clotting factors), and folic acid blood levels should also be monitored by your doctor
  • The most frequently occurring side effects observed with sevelamer carbonate tablets were nausea and vomiting
  • Side effects with sevelamer carbonate powder taken three times a day were similar to those reported for sevelamer carbonate tablets
  • The most common side effects with sevelamer hydrochloride, which contains the same active ingredient as sevelamer carbonate, included: vomiting, nausea, diarrhea, indigestion, abdominal pain, flatulence, and constipation
  • Cases of fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported
  • Take Renvela with meals and adhere to your prescribed diet
  • Talk to your doctor when taking Renvela with other medications
  • Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on Renvela

Please see full Prescribing Information (PDF).