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Indication

Renvela® (sevelamer carbonate) and Renagel® (sevelamer hydrochloride) are used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

Do not use Renvela or Renagel if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate or sevelamer hydrochloride or to any of the ingredients in Renvela or Renagel.

Click here for additional Important Safety Information.

Please see full Prescribing Information for Renvela (PDF) or full Prescribing Information for Renagel (PDF).

On average, most patients pay less than $8/month for their Renvela prescription. Learn more at Renassist.com.

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Understand the role of your kidneys

What do kidneys do?

Your kidneys have several functions in the body. They work to remove waste products and extra fluids in your blood. They also play a role in keeping your bones strong, managing your blood pressure, and balancing phosphorus and calcium.

How is it all related?

When you have chronic kidney disease (CKD) Stage 5, your kidneys can’t do their jobs as well. Minerals like phosphorus and calcium, as well as other substances like PTH can become unbalanced. These minerals and substances affect a number of other functions in the body, like maintaining normal heart, nerve, and muscle function, preserving healthy bones, and other metabolic processes. That’s why it is important to work with your healthcare team to keep these minerals and substances in balance, as there can be a "snowball effect" to many other important functions in your body.

Work with your healthcare team to help keep your mineral levels in a healthy range.

Indication

Renvela® (sevelamer carbonate) and Renagel® (sevelamer hydrochloride) are used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

  • Do not use Renvela or Renagel if you have a history of bowel obstruction or if you are allergic to sevelamer carbonate or sevelamer hydrochloride or to any of the ingredients in Renvela or Renagel.
  • Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation.
  • The most common side effects with sevelamer include vomiting, nausea, diarrhea, upset stomach, abdominal pain, flatulence, and constipation.
  • Cases of itching, rash, fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported.
  • Uncommon cases of difficulty swallowing the Renagel or Renvela tablet have been reported. Talk to your doctor if you have difficulty swallowing medicines in tablet form. Renvela powder for oral suspension may be considered by your doctor if you have a history of difficulty swallowing.
  • Your doctor should monitor bicarbonate and chloride blood levels.
  • Reduced vitamins D, E, and K (clotting factors) and folic acid blood levels may be followed by your doctor.
  • Talk to your doctor when taking sevelamer with other medications.
  • Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on sevelamer.
  • Take sevelamer with meals and adhere to your prescribed diet

Please see full Prescribing Information for Renvela (PDF) or full Prescribing Information for Renagel (PDF).
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The health information contained herein is provided for general education purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.