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Indication for Renvela and Renagel

Renvela® (sevelamer carbonate) and Renagel® (sevelamer hydrochloride) are indicated for the control of serum phosphorus in patients

Important Safety Information for Renvela and Renagel

  • Sevelamer is contraindicated in patients with bowel obstruction.

Click here for additional Important Safety Information.

Please see full Prescribing Information for Renvela (PDF) or full Prescribing Information for Renagel (PDF).

On average, most patients pay less than $7/month for their Renvela prescription. Learn more at Renassist.com.

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Understand the role of your kidneys

What do kidneys do?

Your kidneys have several functions in the body. They work to remove waste products and extra fluids in your blood. They also play a role in keeping your bones strong, managing your blood pressure, and balancing phosphorus and calcium.

How is it all related?

When you have chronic kidney disease (CKD) Stage 5, your kidneys can’t do their jobs as well. Minerals like phosphorus and calcium, as well as other substances like PTH can become unbalanced. These minerals and substances affect a number of other functions in the body, like maintaining normal heart, nerve, and muscle function, preserving healthy bones, and other metabolic processes. That’s why it is important to work with your healthcare team to keep these minerals and substances in balance, as there can be a "snowball effect" to many other important functions in your body.

Work with your healthcare team to help keep your mineral levels in a healthy range.

Indication for Renvela and Renagel

Renvela® (sevelamer carbonate) and Renagel® (sevelamer hydrochloride) are indicated for the control of serum phosphorus in patients

Important Safety Information for Renvela and Renagel

  • Sevelamer is contraindicated in patients with bowel obstruction.
  • Caution should be exercised in patients with dysphagia, swallowing disorders, and severe gastrointestinal (GI) motility disorders, including severe constipation or major GI tract surgery.
  • Common adverse events reported with sevelamer include vomiting, nausea, diarrhea, dyspepsia, abdominal pain, flatulence, and constipation. Other events reported include pruritus, rash, fecal impaction and, less commonly, ileus, bowel obstruction, and bowel perforation.
  • Uncommon cases of difficulty swallowing the Renagel (sevelamer hydrochloride) or Renvela® (sevelamer carbonate) tablet have been reported. Caution should be exercised in these patients and consideration given to using Renvela® (sevelamer carbonate) suspension in patients with a history of difficulty swallowing.
  • Drug-drug interactions may occur with some medications and should be taken into consideration when instructing patients how to take sevelamer.
  • Serum bicarbonate and chloride levels should be monitored.
  • Follow patients for reduced vitamins D, E, and K (coagulation parameters) and folic acid levels.
  • Patients should be informed to take sevelamer with meals and to adhere to their prescribed diets.

Please see full Prescribing Information for Renvela (PDF) or full Prescribing Information for Renagel (PDF).
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The health information contained herein is provided for general education purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.