Renvela® (sevelamer carbonate) is a phosphate binder. If you have Chronic Kidney Disease (CKD) and are on dialysis, you may need to control the amount of phosphorus that stays in your body. Along with a low phosphorus diet and your dialysis treatment, Renvela may be prescribed to help control the phosphorus levels in your blood. This site provides information about CKD, controlling phosphorus and Renvela. You will also find links to other helpful websites.
Genzyme Renvela
Important Treatment Considerations
Renvela® (sevelamer carbonate) is used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis
Do not use Renvela if you have a history of bowel obstruction
Talk to your doctor if you have had digestive tract surgery or other digestive disorders, including severe constipation
Uncommon cases of bowel obstruction and perforation have been reported
Your doctor should monitor bicarbonate and chloride blood levels • Vitamins D, E, K (clotting factors), and folic acid blood levels should also be monitored by your doctor
The most frequently occurring side effects observed with sevelamer carbonate tablets were nausea and vomiting
Side effects with sevelamer carbonate powder taken three times a day were similar to those reported for sevelamer carbonate tablets
The most common side effects with sevelamer hydrochloride, which contains the same active ingredient as sevelamer carbonate, included: vomiting, nausea, diarrhea, dyspepsia, abdominal pain, flatulence, and constipation
Cases of fecal impaction and, less commonly, ileus, bowel obstruction, and bowel perforation have been reported
Take Renvela with meals and adhere to your prescribed diet
Talk to your doctor when taking Renvela with other medications • Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on Renvela