Indication

Renvela (sevelamer carbonate) is used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

• Do not use Renvela if you have a history of bowel obstruction
• Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation
• Uncommon cases of bowel obstruction and perforation have been reported. Your doctor should monitor bicarbonate and chloride blood levels. Vitamins D, E, K (clotting factors), and folic acid blood levels should also be monitored by your doctor
• The most frequently occurring side effects observed with sevelamer carbonate tablets were nausea and vomiting
• Side effects with sevelamer carbonate powder taken three times a day were similar to those reported for sevelamer carbonate tablets
• The most common side effects with sevelamer hydrochloride, which contains the same active ingredient as sevelamer carbonate, included: vomiting, nausea, diarrhea, indigestion, abdominal pain, flatulence, and constipation
• Cases of fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported
• Take Renvela with meals and adhere to your prescribed diet
• Talk to your doctor when taking Renvela with other medications
• Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on Renvela

Please see full Prescribing Information (PDF).