Important Safety Information

Do not use Renvela if you have a history of bowel obstruction. Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation. View Important Safety Information.

About Renvela®

If you have chronic kidney disease (CKD) and are on dialysis, your doctor may prescribe a phosphate binder called Renvela® (sevelamer carbonate) to help remove the extra phosphorus from your body. Unlike other phosphate binders, Renvela does not contain calcium or metal,1 which can stay in your body. It is also not absorbed; therefore, it does not accumulate in your body.

Information on Reimbursement

We’re committed to helping you get coverage for Renvela® (sevelamer carbonate) through Renassist®.

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Learn more about Renvela

Contact Us

Genzyme Therapeutics
500 Kendall Street
Cambridge, MA 02142

Tel: 617-768-9000
Fax: 617-252-7600
Toll free: 800-847-0069

Contact Genzyme

Indication

Renvela (sevelamer carbonate) is used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

  • Do not use Renvela if you have a history of bowel obstruction
  • Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation
  • Uncommon cases of bowel obstruction and perforation have been reported. Your doctor should monitor bicarbonate and chloride blood levels. Vitamins D, E, K (clotting factors), and folic acid blood levels should also be monitored by your doctor
  • The most frequently occurring side effects observed with sevelamer carbonate tablets were nausea and vomiting
  • Side effects with sevelamer carbonate powder taken three times a day were similar to those reported for sevelamer carbonate tablets
  • The most common side effects with sevelamer hydrochloride, which contains the same active ingredient as sevelamer carbonate, included: vomiting, nausea, diarrhea, indigestion, abdominal pain, flatulence, and constipation
  • Cases of fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported
  • Take Renvela with meals and adhere to your prescribed diet
  • Talk to your doctor when taking Renvela with other medications
  • Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on Renvela

Please see full Prescribing Information (PDF).

References

  1. Renvela [package insert]. Cambridge, MA: Genzyme Corp; 2010.