Important Safety Information

• Do not use Renvela if you have a history of bowel obstruction. • Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation. View additional Important Safety Information.

What Is Stage 5D Chronic Kidney Disease?

There are five stages of chronic kidney disease (CKD). Stage 1 has the mildest loss of kidney function, and stage 5 has the most severe. “Stage 5D CKD” means that you have kidney failure and are on dialysis. In order to determine the stage of kidney disease, your doctor will measure your glomerular filtration rate (GFR). As kidney function decreases, your GFR decreases. If you have questions about CKD or GFR, be sure to ask a member of your healthcare team.

Stages Of CKD

Causes of CKD

The most common causes of CKD include:

Symptoms of CKD

In most people, there are no obvious or visible symptoms of CKD until the later stages of the disease. These symptoms vary from person to person and may include:

  • More or less frequent urination
  • Increased tiredness or fatigue
  • Itchy skin
  • Changes in appetite or in the taste of food
  • Nausea or vomiting
  • Swelling of hands or feet
  • Feelings of drowsiness or trouble concentrating
  • Sexual problems or decrease in sex drive

Indication for Renvela

Renvela (sevelamer carbonate) is used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

Download Diet and Lifestyle Tips to Help You Manage Your CKD

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Indication

Renvela is used to control phosphorus levels in patients with chronic kidney disease (CKD) on dialysis.

Important Safety Information

  • Do not use Renvela if you have a history of bowel obstruction.
  • Talk to your doctor if you have had difficulty swallowing or swallowing disorders; or if you have had digestive tract surgery or other digestive disorders, including severe constipation.
  • The most frequently occurring side effects observed with Renvela tablets include nausea and vomiting.
  • Side effects with Renvela powder taken three times a day are similar to those reported for Renvela tablets
  • The most common side effects with Renagel, which contains the same active ingredient as Renvela, include vomiting, nausea, diarrhea, indigestion, abdominal pain, flatulence, and constipation.
  • Cases of itching, rash, fecal impaction and, less commonly, slow bowel activity, bowel obstruction, and bowel perforation have been reported.
  • Uncommon cases of difficulty swallowing the Renvela tablet have been reported. Talk to your doctor if you have difficulty swallowing medicines in tablet form. Renvela for oral suspension may be considered by your doctor if you have a history of difficulty swallowing.
  • Your doctor should monitor your bicarbonate and chloride blood levels.
  • Reduced vitamins D, E, K (clotting factors), and folic acid blood levels may be followed by your doctor.
  • Talk to your doctor when taking Renvela with other medications.
  • Promptly contact your doctor if you experience severe abdominal pain, new or worsening constipation, or other severe intestinal symptoms while on Renvela.
  • Take Renvela with meals and adhere to your prescribed diet.

Please see full Prescribing Information (PDF).

References

  1. National Kidney Foundation. KDOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis. 2003;42(suppl 3):S1-S201.